Highlights from Chemistry Europe, ACES, and GDCh journals

Most Accessed Articles: June 2021

New Synthesis of HIV Drug Dolutegravir Sodium
Practical synthesis route starting from (R)-3-amino-1-butanol

Angewandte Chemie 30/2021: On Target
Overview of the latest issue of Angewandte Chemie

Link Between Alcohol Use and Cancer Risk
An estimated 741,000 new cases of cancer in 2020 were associated with alcohol consumption globally

Tailoring Drug Therapy for Parkinson's Disease
Electrochemical sensor detects the drug levodopa in sweat in real time

How Proteins Influence Calcium Dynamics in Early Alzheimer's Disease
Amyloid-precursor protein (APP) family plays important roles in calcium homeostasis

How Metal–Organic Framework Topology Affects Singlet Oxygen Production
Pore size and porphyrin distribution play important roles in Zr-based MOFs

Detecting COVID-19 Exposure in Near Real Time
Soterius and RMIT University collaborate on a biosensor that can detect the presence of tiny amounts of the SARS-CoV-2 and its variants

Synthesis of Aryl-C-Glycosides
New approach leads to high-yielding synthesis of dapagliflozin, used in diabetes treatment

Overview of Coronavirus Variants
Most mutations of SARS-CoV-2 do not have a noticeable impact on us, but some do – we look at which ones and why