10-step synthetic procedure for the preparation of LSZ102 selenium analogue as highly potent ER-α binder developed

Se Analogue of Breast Cancer Medication

Deep-Tissue Sono-immunotherapy of Orthotopic Pancreatic Cancer
Ultrasound used for the first time for an effective sonodynamic treatment of orthotopic pancreatic cancer in a mouse model

Port of Entry for Coronaviruses
Coronaviruses use monomeric ACE2 molecules as entry receptors on host cells

Half-Sandwich Ruthenium Complex Induces Cancer Cell Death
Immunogenic cell death (ICD) inducers could be useful in melanoma treatment

Gold Complexes as Enhanced Analogues of an Anti-Cancer Drug
[NHC(thiolato)] gold(I) complexes derived from AC1-004, a compound with known activity against human cancer cell lines

First Total Synthesis of Thiamyxins A–C and E
Potent class of RNA-virus-inhibiting (cyclo)depsipeptides

New Vaccine Concept against SARS-CoV-2 Successful in Animals
Vaccine based on a modified "single-cycle" virus that is incapable of replication

Hydrogen Sulfide in Cancer Treatment
Gas-releasing adjuvant improves efficacy of photothermal therapy against cancer

1,3‐Oxazoles as Anticancer Compounds
5-Sulfinyl(sulfonyl)-4-arylsulfonyl-substituted 1,3-oxazoles show promising activity

Clarity with Tiny Drug Crystals
Elusive structure of the antihistamine Levocetirizine determined by electron diffraction