Polyprenylated polycyclic acylphloroglucines which have a range of activities can now be synthesized in just seven steps

Synthesizing Rigid Bicycles

A Better Target for B-Cell Lymphomas
Screening existing library of antagonists for binding affinity toward CD22 identifies new potential treatments for B-cell lymphomas

Therapeutic Target in Breast Cancer
Blocking the expression or activity of a serine protease inhibitor in breast cancer cells could be a potential therapy for breast cancer

Side-effects Effectively Sidelined!
Canadian researchers have found a way to eliminate the liabilities of COX-2-specific inhibitors by introducing NO donor groups

Angewandte Chemie 44/2011: A Combination Made in Heaven
An overview of the latest issue of Angewandte Chemie

Fluorinated MRI Agents
Italian chemists have devised a quick and cheap route to novel polymeric contrast agents for magnetic resonance imaging (MRI)

Most Accessed Articles: September 2011
The most-accessed chemistry articles from ChemPubSoc Europe and GDCh journals for September 2011

A Reality Check for Cancer
Software screens virtual multi-component reaction products which can be rapidly synthesized and undergo a reality check by physical screening

Hollow-Fiber Membranes for Biomedical Applications
Comprehensive comparison of hollow-fiber membranes for 129Xe NMR spectroscopy could improve setup

Triggering Immune Recognition with Long Lipid Chains
Lipid chain length could explain why some pathogens trigger an immune response while others evade immune recognition