Evaluation of platinum–ethacrynic acid conjugates in the treatment of mesothelioma

Chemoresistance in Cancer

Most Accessed Articles: October 2011
The most-accessed chemistry articles from ChemPubSoc Europe and GDCh journals for October 2011

Salinomycin Biosynthesis in Detail
The timing of the key steps in antibiotic and potential anti-cancer compound, salinomycin's biosynthesis has been uncovered

Hydrogen Peroxide Helps Target Cancer
Prodrugs selectively activated by high levels of reactive oxygen species in cancer cells could lead to more active and less toxic treatments

Glass Sponges for Building Bones
Hybrid material made of collagen fibers and silica can be used as a possible substrate for bone tissue culture

Uncovering Invisible Biomarkers
Biomarkers previously invisible to mass spectrometry can now be detected with nanoparticles that concentrate and protect

Inhibiting Biofilm Formation
Small molecules that inhibit biofilm development useful in treatment of chronic biofilm infections in combination with standard antibiotics

40 Years Synthesis of Protoilludanes and Related Sesquiterpenes
Sesquiterpenes have fascinating biological properties, members of this class are interesting for the development of new antibiotics

The Eye of the Beholder
New calculations explain why vision uses the 11-cis form of the pigment retinal, rather than any of the other possible forms

A Hot New Development: Photoacoustic Imaging
Photoacoustic Tomography, or short PAT, is a new acronym to remember! The technology has received broad interest for clinical translation