A fluorogenic alkaline phosphatase probe detects abnormal levels of alkaline phosphatase (ALP) in serum, indicating liver disease

Replacing Clinical Colorimetry Methods for Liver Disease Detection

Most Accessed Articles: May 2023
Highlights from Chemistry Europe, ACES, and GDCh journals

Angewandte Chemie 25/2023: Solutions
Overview of the latest issue of Angewandte Chemie

Se Analogue of Breast Cancer Medication
10-step synthetic procedure for the preparation of LSZ102 selenium analogue as highly potent ER-α binder developed

Deep-Tissue Sono-immunotherapy of Orthotopic Pancreatic Cancer
Ultrasound used for the first time for an effective sonodynamic treatment of orthotopic pancreatic cancer in a mouse model

Port of Entry for Coronaviruses
Coronaviruses use monomeric ACE2 molecules as entry receptors on host cells

Half-Sandwich Ruthenium Complex Induces Cancer Cell Death
Immunogenic cell death (ICD) inducers could be useful in melanoma treatment

Gold Complexes as Enhanced Analogues of an Anti-Cancer Drug
[NHC(thiolato)] gold(I) complexes derived from AC1-004, a compound with known activity against human cancer cell lines

First Total Synthesis of Thiamyxins A–C and E
Potent class of RNA-virus-inhibiting (cyclo)depsipeptides

New Vaccine Concept against SARS-CoV-2 Successful in Animals
Vaccine based on a modified "single-cycle" virus that is incapable of replication