Series of biphenyl α-D-mannosides could prevent and treat urinary tract infections (UTIs) by blocking bacterial adhesion to host cells
Bugs Can't Get a Firm Grip on UTIs
Ring Expansion of Isatins
Biologically active nitrogen-containing heterocycles have been synthesized through controlled ring expansion of isatin derivatives
Crystal Engineering of Stable Temozolomide
Antitumor prodrug temozolomide is more stable towards decomposition and discoloration with organic acid cocrystals
Gene Therapy Slows Ageing
First proof-of-principle that telomerase gene therapy is a feasible and potentially safe approach to improve healthy lifespan of older organisms
A Dangerous Role of a Small Aminoacid
Glycine biosynthesis sustains rapid cancer cell proliferation
Angewandte Chemie 23/2012: The Art of Abstraction
An overview of the latest issue of Angewandte Chemie
Organic Electronics Help Control Muscles
Chemical chips containing logic gates, such as NAND gates, allow for chemical control of muscles
Castor Oil: Old and New
Castor oil induces laxation and uterus contraction via ricinoleic acid activating prostaglandin EP3 receptors
Imaging of Flowing Blood Cells
Spectrally encoded flow cytometry (SEFC), for high resolution imaging of flowing red and white blood cells in human patients
New Polymer for New Vision
Injectable polysiloxane gels could be used to create an adjustable replacement lens for people with cataracts or presbyopia