Previously unknown serine protease forms part of the antibacterial defense arsenal of neutrophil granulocytes

New Immune Defence Enzyme

Antiviral Drug Strategies
Erik De Clercq' book, Antiviral Drug Strategies, is reviewed by Thomas W. Bell, USA

Angewandte Chemie 18/2012: No End in Sight
An overview of the latest issue of Angewandte Chemie

Simulated Digestion for Better Drug Delivery
Nanomaterial made from lipids and silicon dioxide improves absorption of pharmaceuticals by imitating the food effect

Graphene Capsules
A novel drug-delivery system can be built using capsules of composite graphene oxide and poly(allylamine hydrochloride)

Effective siRNA Delivery
siRNA polymerized for the first time in hydrogel particles for controlled intracellular delivery

New Biprivileged Molecular Scaffolds
Compounds with several heteroaromatic functionalities present multiple rigid privileged structures for drug discovery

Most Accessed Articles: March 2012
The most-accessed chemistry articles from ChemPubSoc Europe and GDCh journals for March 2012

Enhanced Contrast Media for Magnetic Resonance Imaging (MRI)
Micelles with enhanced chemical exchange saturation transfer (CEST) sensitivity synthesized

Enhanced Solubility and Bioactivity of Pharmaceuticals
Acyclic cucurbit[n]uril molecular containers enhance the solubility and bioactivity of poorly soluble pharmaceuticals