Orexin receptor antagonist developed by Merck and currently in phase II trials promising for treating insomnia

A new lead for antimalarial drugs has been developed through structure-activity studies on the GlaxoSmithkline database

Chip-based method for the rapid, sensitive isolation of rare cells in blood

The first enantioselective total synthesis of the toxin (S)-bisoranjidiol, a bisanthraquinone, has been achieved by US chemists

An overview of the latest issue of Angewandte Chemie

The most-accessed chemistry articles from ChemPubSoc Europe and GDCh journals for January 2012

New insights into the way mammalian sirtuin proteins function could offer a clearer understanding of the aging process

Overview of the chemical synthesis of cardiotonic steroid glycosides – recently neglected, but promising field

Iron nanoparticles with an iron oxide shell resist oxidation and maintain magnetic properties needed for biomedical applications

(–)-7S-OH-lentiginosine has been efficiently synthesized and is an apoptosis inducer that has low cytotoxicity toward healthy cells