Biologically active nitrogen-containing heterocycles have been synthesized through controlled ring expansion of isatin derivatives

Antitumor prodrug temozolomide is more stable towards decomposition and discoloration with organic acid cocrystals

First proof-of-principle that telomerase gene therapy is a feasible and potentially safe approach to improve healthy lifespan of older organisms

Glycine biosynthesis sustains rapid cancer cell proliferation

An overview of the latest issue of Angewandte Chemie

Chemical chips containing logic gates, such as NAND gates, allow for chemical control of muscles

Castor oil induces laxation and uterus contraction via ricinoleic acid activating prostaglandin EP3 receptors

Spectrally encoded flow cytometry (SEFC), for high resolution imaging of flowing red and white blood cells in human patients

Injectable polysiloxane gels could be used to create an adjustable replacement lens for people with cataracts or presbyopia

An overview of the latest issue of Angewandte Chemie