Simple and compact synthesis of a tricyclic resorcinol could provide route to novel analogs of conformationally restricted cannabinoids

Access to Cannabinoids

Hypusine Keeps Tumor Away
Hypusine synthesis prevents development of lymphomas by relying on the polyamine–hypusine axis

Richard Neidlein (1930 – 2012)
Richard Neidlein, Heidelberg University, Germany, passed away on July 20

What Would Happen Without PSA Testing? Cancer Press Release
Is prostate specific antigen (PSA) testing an ineffective screen for prostate cancer? Or does it help save lives?

Angewandte Chemie 31/2012: A Bright Image
Overview of the latest issue of Angewandte Chemie

Barking up the Right Tree
Three new natural products from the bark of a Vietnamese evergreen tree show cytotoxic activity against cancer cells

Potent and Selective c-Met Inhibitor
O-linked triazolotriazines are novel c-Met inhibitors displaying efficacy and selectiveness for cancer cell lines

Timely Delivery
Ribonucleoside 3'-phosphates as pro-moieties for the timed release of orally available drugs

Angewandte Author Profiles July 2012
K. Anker Jorgensen, D. Stalke, A. Osuka, N. Mizuno, A. Ajayaghosh, M. Jansen, D. A. Leigh, B. M. Trost, and others are interviewed this month

Angewandte Chemie 30/2012: No Longer in Its Infancy
Overview of the latest issue of Angewandte Chemie