A two-directional total synthesis has been used by US chemists to construct microbial molecules with anticancer properties
Double-Edged Synthesis
Blowing Bubbles to Kill Cancer
Liposomes containing ammonium bicarbonate release carbon dioxide bubbles that induce the killing of cancer cells
Natural Antibiotic Kills Tuberculosis Bacterium
Natural product secreted by a soil bacterium shows promise as a new drug to treat tuberculosis
How to Model a Pain Reliever
New results can help scientists understand the working mechanism of anesthetics
Emil Fischer Medal for H. Waldmann
Professor Herbert Waldmann, Germany, is the recipient of the 2012 Emil Fischer Medal, awarded for work in organic chemistry
A Benzodiazepine Sedates Leukemia
The benzodiazepine Ro5-3335 reduces the development of core binding factor leukemias by inhibiting RUNX1-CBFβ interactions
Who's Next? 2012 Nobel Prize in Chemistry
Make your predictions for the 2012 Nobel Prize in Chemistry here
Improving Drug Delivery to the Brain
Sphingolipid analogs improve drug delivery across the blood-brain barrier by targeting the transporter P-glycoprotein
Glycosilated Dendrimers Protect the Gut
A glycosilated polypropyletherimine dendrimer defends gut wall’s integrity during infectious inflammatory diarrhea
Rhenium-Centric Reverse Turn Mimics
Re complex provides access to reverse-turn mimics for diagnostic and therapeutic radiopharmaceuticals