US scientists have developed a small molecule which antagonizes the transcriptional factor HIF-2 by inducing allosteric changes
Blocking Hypoxia Inducible Factors Allosterically
A Dangerous Transfer of Methyl Groups
Nicotinamide N-methyltransferase promotes tumorigenesis by regulating the methylation potential of cancer cells
Green Ibuprofen
Safer solvents can be used in the synthesis of ibuprofen–nicotinamide co-crystal for the production of a more water soluble formulation
Most Accessed Articles: February 2013
The most-accessed chemistry articles from ChemPubSoc Europe and GDCh journals for February 2013
Mouthwash to Fight Cancer?
Oral disinfectants induce apoptosis in human oral tumor cells
Can the Pharmaceutical Industry Restore its Broken Image?
John LaMattina, former President, Pfizer Global R&D, discusses his book on how and why the pharma industry is devalued and distrusted
It’s ALL About a Cytosolic 5’-Nucleotidase
Cytosolic 5’-nucleotidase II hyper-activation causes drug resistance and relapse in acute lymphoblastic leukemia (ALL) patients
Anticancer Graphene
Graphene nanosheet coated with silica shows synergistic chemo-photochemical effect in targeting otherwise difficult-to-treat cancer
Meyer-Galow Prize for Susanne Röhrig
Susanne Röhrig, Bayer HealthCare, is the first recipient of the Meyer-Galow Prize for chemistry industry
Angewandte Chemie Celebrates 125 Years
With a packed program of highest caliber scientists around the globe celebrated the journal with an exciting and inspiring day