(R)-2-hydroxyglutarate promotes acute myeloid leukemias’ development but its effects can be pharmacologically blocked

Sipholenol analogues revealed as novel scaffolds for drugs that inhibit breast cancer cell migration and invasion

cGAMP synthase senses microbic DNA molecules and acts as an alarm signal which activates immune defenses

With blockbuster drugs falling off the patent cliff, open innovation is being hailed as the key element to drive future success

Holiday overindulgence and catecholamines resulting from stress or excitement can can trigger arrhythmias and sudden cardiac death

Chinese researchers created enzymatic nanocomplexes which can be used to counteract and prevent alcohol intoxication

Investment round to raise EUR 1.7m of capital to develop a range of drug compounds that can address some of the most acute diseases

Elegant way to limit the number of biochemical experiments to predict the toxicity of a drug candidate won Molecular Informatics Best Paper Award

The most-accessed chemistry articles from ChemPubSoc Europe and GDCh journals for January 2013

Behavioral changes of perch because their brains have the same kind of target receptor as human brains for drug Oxazepam