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Picture Competition – A Year in the Lab: The Chemist’s View
A Safe and Good Night’s Sleep
DORA-22, an orexin receptor antagonist, effectively treats insomnia without impairing memory and attention
Acetyl or Myristoyl: That is the Question
US scientists revealed that the sirtuin SIRT6 is not a deacetylase but a long-chain fatty-acyl hydrolase
Preventing Geldanamycin’s Toxicity
Novel 19-substituted benzoquinone ansamycins inhibit heat shock protein 90 without causing toxic effects in vitro
9th European Congress of Chemical Engineering (ECCE)
Europe’s largest science and business congress on Chemical Engineering and Applied Biotechnology was held in Den Haag
Long Wavelength Fluorescein Analogues
Modification of fluorescene leads to analogues with better photo-physical characteristics
Lactimidomycin – No Effect on Cell Motility but Still Cytotoxic
Synthesis and biological re-evaluation of the cytotoxic effects of Lactimidomycin and its progeny in cancer cells
Machine-Assisted Flow Synthesis
Flow-based syntheses to accelerate multistep routes to highly complex, medically relevant compounds have been evaluated
Novel Therapeutic Target for Pancreatic Cancer
A non-canonical metabolism of the amino acid glutamine sustains pancreatic ductal adenocarcinoma’s growth
Most Accessed Articles: March 2013
The most-accessed chemistry articles from ChemPubSoc Europe and GDCh journals for March 2013