Enzymatically synthesized unnatural amino acid offers new possibilities in protein research

New Unnatural Amino Acid for Protein Engineering

Malaria: One Drug, Double Action
The 4(1H)-quinolone derivative ELQ-300 acts against the asymptomatic and symptomatic stages of malaria infection

Flame Resistants Expose Office Workers
Exposure of adult office workers to the flame retardant tris(1,3-dichloro-2-propyl) phosphate (TDCPP) measured

Animal-to-human Transmission of Bacterial Pathogens
Animal-to-human transmission of the methicillin-resistant Staphylococcus aureus (MRSA) confirmed

Nanoparticles for Broken Hearts
Novel SiO2-based nanoparticles allow to monitor the therapeutic transplant of stem cells into damaged cardiac tissues

Cancer Fighting Fish: Source of New Drugs?
The commercial fish Pacific cod contains a glycopeptides able to block the metastasis of pancreatic cancer cells

Blocking Hypoxia Inducible Factors Allosterically
US scientists have developed a small molecule which antagonizes the transcriptional factor HIF-2 by inducing allosteric changes

A Dangerous Transfer of Methyl Groups
Nicotinamide N-methyltransferase promotes tumorigenesis by regulating the methylation potential of cancer cells

Green Ibuprofen
Safer solvents can be used in the synthesis of ibuprofen–nicotinamide co-crystal for the production of a more water soluble formulation

Most Accessed Articles: February 2013
The most-accessed chemistry articles from ChemPubSoc Europe and GDCh journals for February 2013