DORA-22, an orexin receptor antagonist, effectively treats insomnia without impairing memory and attention

US scientists revealed that the sirtuin SIRT6 is not a deacetylase but a long-chain fatty-acyl hydrolase

Novel 19-substituted benzoquinone ansamycins inhibit heat shock protein 90 without causing toxic effects in vitro

Europe’s largest science and business congress on Chemical Engineering and Applied Biotechnology was held in Den Haag

Modification of fluorescene leads to analogues with better photo-physical characteristics

Synthesis and biological re-evaluation of the cytotoxic effects of Lactimidomycin and its progeny in cancer cells

Flow-based syntheses to accelerate multistep routes to highly complex, medically relevant compounds have been evaluated

A non-canonical metabolism of the amino acid glutamine sustains pancreatic ductal adenocarcinoma’s growth

The most-accessed chemistry articles from ChemPubSoc Europe and GDCh journals for March 2013

Difluorosialic derivatives are a novel class of anti-influenza medicaments acting against drug-resistant viral strains