Separation of dicarboxylic acids through solid-state molecular recognition and mechanochemistry

Separation of Isomers by Milling

Photochemical Control of Pain
US researchers discovered a small molecule which renders pain transmitting neurons sensitive to light

Picture Competition – A Year in the Lab: The Chemist’s View
Submit your outstanding photo and have the chance to be selected for a calendar and win one of 12 exciting prizes

A Safe and Good Night’s Sleep
DORA-22, an orexin receptor antagonist, effectively treats insomnia without impairing memory and attention

Acetyl or Myristoyl: That is the Question
US scientists revealed that the sirtuin SIRT6 is not a deacetylase but a long-chain fatty-acyl hydrolase

Preventing Geldanamycin’s Toxicity
Novel 19-substituted benzoquinone ansamycins inhibit heat shock protein 90 without causing toxic effects in vitro

9th European Congress of Chemical Engineering (ECCE)
Europe’s largest science and business congress on Chemical Engineering and Applied Biotechnology was held in Den Haag

Long Wavelength Fluorescein Analogues
Modification of fluorescene leads to analogues with better photo-physical characteristics

Lactimidomycin – No Effect on Cell Motility but Still Cytotoxic
Synthesis and biological re-evaluation of the cytotoxic effects of Lactimidomycin and its progeny in cancer cells

Machine-Assisted Flow Synthesis
Flow-based syntheses to accelerate multistep routes to highly complex, medically relevant compounds have been evaluated