A concise, step-economical synthesis of natural products, tatanans A–C, and their biological activity is examined
Reinvestigating Tatanans A–C
New Unnatural Amino Acid for Protein Engineering
Enzymatically synthesized unnatural amino acid offers new possibilities in protein research
Malaria: One Drug, Double Action
The 4(1H)-quinolone derivative ELQ-300 acts against the asymptomatic and symptomatic stages of malaria infection
Flame Resistants Expose Office Workers
Exposure of adult office workers to the flame retardant tris(1,3-dichloro-2-propyl) phosphate (TDCPP) measured
Animal-to-human Transmission of Bacterial Pathogens
Animal-to-human transmission of the methicillin-resistant Staphylococcus aureus (MRSA) confirmed
Nanoparticles for Broken Hearts
Novel SiO2-based nanoparticles allow to monitor the therapeutic transplant of stem cells into damaged cardiac tissues
Cancer Fighting Fish: Source of New Drugs?
The commercial fish Pacific cod contains a glycopeptides able to block the metastasis of pancreatic cancer cells
Blocking Hypoxia Inducible Factors Allosterically
US scientists have developed a small molecule which antagonizes the transcriptional factor HIF-2 by inducing allosteric changes
A Dangerous Transfer of Methyl Groups
Nicotinamide N-methyltransferase promotes tumorigenesis by regulating the methylation potential of cancer cells
Green Ibuprofen
Safer solvents can be used in the synthesis of ibuprofen–nicotinamide co-crystal for the production of a more water soluble formulation