Introduction of a sulfoximine group into anticancer candidates shows that sometimes sticking to the unconventional pays off

Discovery of Unexpectedly Active Group

Exploiting Structural Differences in Serotonin Receptors
Serotonin receptors present structural differences which can be used to design agonistic drugs devoid of side effects

Health Warnings for Shampoos?
Personal care products carry no hazardous symbols as they are explicitly excluded from the regulation for labeling of chemicals

Hope for Hepatitis Drug
A straightforward synthesis of an antiviral drug, entecavir, to treat hepatitis B has industrial scale-up potential

New Route to Anticancer Agent Quinocarcin
Synthesis of quinocarcin through a convergent strategy based on Sonogashira coupling and gold(I)-catalyzed hydroamination

Awakening to New Drugs against Sleeping Sickness
Structure–activity relationships and optimization of triazine nitriles as rhodesain inhibitors

Mixing Water and Oil: A Magic Process
A bottom-up process for making dodecane-in-water nanoemulsions in just ten seconds has been reported

Magnetic Nanoparticles Detect Pathogens
A novel iron oxide nanoparticle-based system detects pathogens with high sensitivity, specificity, and rapidity

Silencing a Tumorigenic Catalyst
Novel isocitrate dehydrogenases 1 and 2 inhibitors prevent the growth of brain and blood tumors

Nanomachine Drug Delivery
A sensing–actuating nanomachine based on Janus Au–mesoporous silica nanoparticles for enzyme-controlled cargo release