A new series of ruthenium complexes that act as histone deacetylase (HDAC) inhibitors show promise as anticancer agents

Next-Generation of Histone Deactylase Inhibitors

Extracting the Medicine from Traditional Chinese Medicine
Isolated compounds from Chinese medicine often show physiological activity. One such compound from Gansong has been identified

Roughing up Smoothened
A second-generation Smoothened (Smo) antagonist has shown excellent efficacy in rodent tumor models

History of Cyclotides
Cyclotides are head-to-tail cyclic peptides in plants

100th Birthday: Mildred Cohn
A biochemist who overcame religious and sexual discrimination

Modern Tools for the Synthesis of Complex Bioactive Molecules
Application of innovative modern synthetic methods and techniques for preparing natural products and other compounds of biological and pharmacological interest

2012 ISI Journal Impact Factors
Excellent Results for Wiley and Wiley-VCH in the 2012 Journal Citation Reports

Alcohol? It is just a Memory
The immunosuppressant drug rapamcyin destroys drinking-associated memories and helps reducing alcoholic relapse

Rendering Medical Implants Biocompatible
Poly(carboxybetaine methacrylate) hydrogels can be used to increase the biocompatibility of medical implants

Guess the Chemist (19)
Can you guess the famous scientist from the description?