Screening of a chemical library of 40,000 natural products showed that aniquinazoline B, a fungal natural product, activates the µ-opioid receptor

Pain Relief Without the Usual Risks of Opioids

Mechanochemical Path to NO-Releasing Drugs
Strategy using 1,1’-carbonyldiimidazole (CDI) as an activating agent allows for a straightforward synthesis of two bioactive iminosydnones

Green Late-Stage Functionalization of Tryptamines
Efficient and rapid protocol for the oxidative halocyclization of tryptamines works even with household bleach

Most Accessed Articles: May 2024
Highlights from Chemistry Europe, ACES, and GDCh journals

Luisa De Cola Awarded 2024 Centenary Prize for Chemistry and Communication
Her groundbreaking research on creating photophysically active materials and nanostructures for healthcare applications and her communication skills honored

Iodine-Substituted Polydiacetylene Nanospheres for Phototherapy
Improved therapeutic efficacy for both photodynamic therapy and photothermal therapy

Maternal Dairy Fat Intake Linked to Improved Psychomotor Development in Lemurs
How do different diets in gray mouse lemurs during gestation and lactation affect on their offspring?

Marine Natural Product Activates Opioid Receptor
Large chemical database screened for candidates for safer pain medications

The Misjudgment of Heroin
From cure-all to most notorious drug of the 20th century

Drugs from a Chemical Perspective
A growing collection of articles looking at substances like nicotine, LSD, and marijuana from a chemical perspective, exploring how they are used and why, etc.