Discussing future visions at Merck’s 350th anniversary with eminent people

Stimulate Curiosity

Genomic Damage
CRISPR–Cas9 produces unwanted DNA deletions and mutations

Antimicrobial Nanostructures Made from Short Peptides
Short‐peptide amphiphile nanostructures deliver antibacterial metal ions

Most Accessed Articles: June 2018
Highlights from ChemPubSoc Europe, ACES, and GDCh journals

Improved Antimalaria Drug
Conjugation of organometallic groups to sulfadoxine changes the drug's activity

Bioactivity of Artemisinin Derivatives
Artemisinin-derived dimers, trimers, and dendrimers studied for their antimalarial/antiviral activity

Direct Synthesis of Polycyclic Tropanes
Single step mechanism to form complex polycyclic tropanes with high yields and stereoselectivities

Angewandte Chemie 28/2018: The Value of Truth
Overview of the latest issue of Angewandte Chemie

Improved Delivery of Anticancer Drugs in Liposomes
Hydrogen bonding plays a crucial role in liposomal formulations

Blocking Cell-to-Cell Signaling to Kill Bacteria
Structural transitions change the shape of a binding pocket of an enzyme; finding can be used to develop specific path blockers