Markus Kraft on the intersection of AI and chemistry, knowledge engineering and machine learning, their applications, challenges and successes, as well as his World Avatar Project

A Tsunami of Innovations Is Ahead of Us

A Direct Route to Heavy Olefins
Selective production of extra-heavy olefins via the overall conversion of CO and water

α-Amination of Amides and Ketones
Straightforward transfer of a free amino group from a commercially available nitrogen source

Angewandte Chemie 19/2023: Access Points
Overview of the latest issue of Angewandte Chemie

Cobalt(I) Complexes with an N-Heterocyclic Silylene for Olefin Hydrogenation
Co(I) hydride complex exhibits high catalytic efficiency and good chemoselectivity

Coupling of 7-Azaindoles with Thiophenes
Rhodium(III)-catalyzed cross-dehydrogenative coupling reaction

Photochemical Functionalization of Strong C–H Bonds
Convenient approach using allyl bromides and sodium fluoride

Functionalized Zigzag-Type Hydrocarbon Belts
Compounds with functionalized eight-membered rings can serve, e.g., as selective hosts for cesium ions

Cascade Heck-Alkylation Reaction Gives α-Alkyl Tryptophans
Reaction of amino acid esters with N-(2-iodophenyl)allenamides gives optically active products

Nonstabilized Carbenes Used for Asymmetric Cyclopropanations
Transition metal carbenoids generated from dihaloalkane precursors