Synthesis and biological characterization of amidopropenyl hydroxamates as histone deacetylase inhibitors for cancer treatment
HDAC Inhibitors
Digging Deep
Journal of Physical Organic Chemistry presents a "Symposium in Print on Tunneling in Chemical and Biological Reactions"
Factors Behind the Impact
With new impact factors being announced, ChemViews takes a look at their calculation, controversy and usage.
Future Visions of Chemistry: Koop Lammertsma
"Gone is gone. There are no alternatives." - Interview with Koop Lammertsma, VU University, the Netherlands.
Future Visions of Chemistry: Ben Davis
"It puzzles me why some chemists do not see chemistry as the big science." - Interview with Ben Daivis, University of Oxford, UK
Asymmetric Antimalarial
An asymmetric total synthesis of the natural product erythro-8-O-4'-neolignan, machilin C, and its analog has been developed.
Blue Bananas
Unique blue fluorescent chlorophyll decomposition products in banana leaves not mere detoxification products
Cancer and Crabs
Building multifunctional chiral building blocks from materials like D-glutamic acid opens up synthetic routes to natural products.
Scaffold Synthesis
The enantioselective synthesis of alkaloids, using a tricyclic (R)-phenylglycinol-derived lactam scaffold is reported.
Loosening the Purse Strings
The EU will add EUR 40 million to its contribution to the international Cooperation in Science and Technology (COST) program.