The hydantoin scaffold found in a range of drugs can be formed simply from ureas and thioureas tethered to amides

New Route to Aminohydantoins

Chlorosulfolipids
Summary of the progress in the synthesis and study of the fascinating natural products chlorosulfolipids

Overcoming the Solubility Problem of Lignin
Catalytic oxidation of benzyl alcohols and lignin is achieved by tuning solubility, cocatalyst, and recyclable catalyst

80th Birthday: Ekkehard Winterfeldt
Ekkehard Winterfeldt, renowned synthetic chemist and former GDCh President, celebrates his 80th birthday

Angewandte Chemie 20/2012: A Trip through the World of Chemistry
An overview of the latest issue of Angewandte Chemie

From Radicals to γ-Lactones
A one-pot sequence of radical cyclization and Oppenauer-type oxidation gives gamma-lactones in high yields

The Future of Medicinal Chemistry
T. Hoffmann and R. Metternich, F. Hoffmann−La Roche Ltd., look at potential areas for drug R&D outside traditional medicinal chemistry

Alcohol-Butadiene Hydrohydroxyalkylation
Direct redox-triggered carbon-carbon coupling sets stage for development of catalysts that exhibit enhanced stereoselectivities

Angewandte Chemie 19/2012: The Secret of Print
An overview of the latest issue of Angewandte Chemie

Unnatural Amino Acids
Engineering methylaspartate ammonia lyase has helped researchers with the asymmetric synthesis of unnatural amino acids