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Picture Competition – A Year in the Lab: The Chemist’s View

Preventing Geldanamycin’s Toxicity
Novel 19-substituted benzoquinone ansamycins inhibit heat shock protein 90 without causing toxic effects in vitro

Lactimidomycin – No Effect on Cell Motility but Still Cytotoxic
Synthesis and biological re-evaluation of the cytotoxic effects of Lactimidomycin and its progeny in cancer cells

Assisting C−H Activation
Detailed study into the mechanism for carboxylate-assisted C−H bond activation at Pd(IV) centers has been undertaken

Green Oxidations on Graphene
Graphene as an aerobic oxidation carbocatalyst derived from natural resources

Machine-Assisted Flow Synthesis
Flow-based syntheses to accelerate multistep routes to highly complex, medically relevant compounds have been evaluated

Most Accessed Articles: March 2013
The most-accessed chemistry articles from ChemPubSoc Europe and GDCh journals for March 2013

Novel Anti-influenza Drugs
Difluorosialic derivatives are a novel class of anti-influenza medicaments acting against drug-resistant viral strains

Stöber Method for Polymer Coating Core-Shell Nanoparticles
Modified emulsion polymerization gives excellent control of the shape and thickness of shells of core-shell nanoparticles

Bicycling the Square
An organic square can be converted to tiny bicyclic compound through an intramolecular rearrangement