Bottom-up, stepwise synthesis allows construction of peripherally functionalized hexaphyrins with unsubstituted meso carbon atoms

Turning Around the Synthesis of Hexaphyrins

Cryptophane Proves Good Host
A strategy for the easy synthesis of a water-soluble cryptophane-111 derivative has been developed

First Natural Product from Marine Myxobacteria
Salimabromide is the first natural product to be isolated from the Plesiocystis/Enhygromyxa clade of marine myxobacterium

Bravo for Brevisamide
Chemists in India have devised a formal stereoselective synthesis of the unprecedented, marine monocyclic ether alkaloid (–)-brevisamide

A Drug Discovery Detective Story
Biological activity of small-molecule RNA polymerase (RNAP) inhibitors revealed to come from polymeric impurity

Most Accessed Articles: April 2013
The most-accessed chemistry articles from ChemPubSoc Europe and GDCh journals for April 2013

French Chemical Society National and Bi-national Awards
The winners of the annual national and bi-national prizes of the SCF include Klaus Müllen, Santiago Alvarez Reverter, and Samir Zard

Exploiting Structural Differences in Serotonin Receptors
Serotonin receptors present structural differences which can be used to design agonistic drugs devoid of side effects

New Stimuli Responsive Supramolecular Gels
Photoresponsive supramolecular gels that incorporate an azobenzene unit into peptide side chains are reported

Hope for Hepatitis Drug
A straightforward synthesis of an antiviral drug, entecavir, to treat hepatitis B has industrial scale-up potential