Chemists in India have devised a formal stereoselective synthesis of the unprecedented, marine monocyclic ether alkaloid (–)-brevisamide
Bravo for Brevisamide
A Drug Discovery Detective Story
Biological activity of small-molecule RNA polymerase (RNAP) inhibitors revealed to come from polymeric impurity
Most Accessed Articles: April 2013
The most-accessed chemistry articles from ChemPubSoc Europe and GDCh journals for April 2013
French Chemical Society National and Bi-national Awards
The winners of the annual national and bi-national prizes of the SCF include Klaus Müllen, Santiago Alvarez Reverter, and Samir Zard
Exploiting Structural Differences in Serotonin Receptors
Serotonin receptors present structural differences which can be used to design agonistic drugs devoid of side effects
New Stimuli Responsive Supramolecular Gels
Photoresponsive supramolecular gels that incorporate an azobenzene unit into peptide side chains are reported
Hope for Hepatitis Drug
A straightforward synthesis of an antiviral drug, entecavir, to treat hepatitis B has industrial scale-up potential
New Route to Anticancer Agent Quinocarcin
Synthesis of quinocarcin through a convergent strategy based on Sonogashira coupling and gold(I)-catalyzed hydroamination
Thermally Stable Silver-Containing Ionic Liquids
Thermally stable ionic liquids prepared for the electrodeposition of metallic silver with high deposition rates
Fluorescence Anion Sensors
Incorporating a fluorescent probe into a polymeric matrix gives a sensor array that can recognize eight different analytes