Combining a lysosome-targeted near-infrared (NIR) probe with AI-driven image interpretation offers a scalable platform for high-resolution monitoring of lysosomal function

An NIR Fluorescent Probe for Assessing Lysosomal Function

🧪 Article Highlight: Calcium Joins the Organometallic Toolbox
French chemists capture and study long-sought di-n-butylcalcium, showing it can perform useful reactions when kept ice-cold

Cascade Chemistry Opens a New Path for Acetone Arylation
A new Pd-catalyzed cascade reaction achieves selective mono-α-arylation of acetone using diaryliodonium salts and alkene

Protein–Starch Clusters: A Strategy for Designing Diabetes-Fighting Foods
How wheat proteins control starch digestion revealed: Key mechanisms for designing low-glycemic foods with transformative diabetes-fighting potential

🧪 Article Highlight: Predicting Molecular Aggregate Behavior of Organic Chromophores
Walter Thiel Medal winner Felix Plasser, UK, and colleagues studied how molecules in solid organic materials interact, focusing on the influence of π-stacking and explaining under what circumstances their chromophores couple to form H- or J-aggregates

Intrinsic Luminescence of Pure Organic Mono- and Di-Radicals in Aggregated States
Strategy enables efficient organic radical luminescence in solids by suppressing harmful interactions, aiding solid-state lighting

Chemistry – A European Journal Readers’ Choice 2025
Collection that showcases the most popular articles published in the journal in 2023 and 2024 in terms of citations, downloads, social media activity

Fe(III)-Directed 15-Step Domino Oligomerization
FeCl3 enables a record 15-step domino reaction with benzothiazole methanol, forming novel fluorescent tricyclic aggregates

Angewandte Chemie Update
Just published articles from Angewandte Chemie, the flagship journal of the German Chemical Society (GDCh)

A Simple Route to Stable Antiaromatic Compounds from Diazaporphyrins
Hiroshi Shinokubo, Japan, and his coauthors discovered a simple reductive dimethylation that transforms Ni(II) 5,15-diazaporphyrins into stable, antiaromatic porphyrinoids