Total synthesis of marine antitumor agents trabectedin and lurbinectedin

From Sea to Lab

Organocatalyzed Aerobic Oxidation of Aldehydes
Efficient path to carboxylic acids under mild conditions

Tailored Ionic Liquids with Palladate Counterions
New class of tunable aryl alkyl ionic liquids (TAAILs)
![Chlorination of Highly Strained Bicyclo[1.1.1]pentane Derivative](https://www.chemistryviews.org/wp-content/uploads/legacy/common/images/thumbnails/source/168f171bc64.jpg)
Chlorination of Highly Strained Bicyclo[1.1.1]pentane Derivative
Selective radical chlorination

Organic 2D Materials Made by Self-Assembly
Cucurbit[8]uril-based material conducts electricity only in one direction

Anti-Markovnikov Hydroarylation of Alkenes
Nickel-catalyzed reductive cross-coupling of alkenes and aryl halides

Turning a MOF into Glass
Flux melting creates new form of the common metal-organic framework (MOF) ZIF-8

Radical Difluoromethoxylation of Arenes
Redox-active difluoromethoxylating reagent for the conversion of unactivated arenes under photocatalytic conditions

Grand Prix 2018 de la Fondation de la Maison de la Chimie
Thomas Ebbesen, University of Strasbourg, France, and Susumu Kitagawa, University of Kyoto, Japan, honored

Photoredox-Catalyzed Alkenylation of Organosulfur Compounds
Benzylsulfonium salts and styrene derivatives were coupled under blue LED light