Simple blocking group based on inexpensive maleic acid provides regioselectivity

Selective C-4 Alkylation of Pyridines

Fluorination of 2H-Indazoles
Simple functionalization using N-fluorobenzenesulfonimide (NFSI) in water

Controlling Asymmetry for Drug Synthesis
Iridium-catalyzed hydrogen addition gives plant- and insect-based natural substances

The First Molecule Stories
We are still looking forward to your stories, but already want to share some molecules and the first book prize winners with you

Pyrrole-Embedded Graphene Nanoribbons
Linear and helical graphene nanoribbons with pyrrole units synthesized via photochemical cyclodehydrochlorination

85th Birthday: Karl O. Christe
Inorganic chemist known for his work on polynitrogen compounds and fluorine chemistry

Total Synthesis of (+)-Ambiguine G
Chlorinated pentacyclic indole alkaloid prepared in ten steps

BODIPY-Decorated Tetraphenylethylenes
New dye conjugates with useful emission properties and possible uses as photosensitizers

3-Silaazetidine Synthesized from Air-Stable Precursor
Small silacycle can be used in palladium-catalyzed ring expansion reactions

Molecule Story: 2,6-Diisopropylphenol
Miklos Simonyi, Hungary, is fascinated by the structure of this molecule