Engineered variant of the transcription factor CarH used for non-native radical cyclization reactions

Biocatalyzed alcohol oxidation and chemocatalyzed Pictet-Spengler annulation give tetrahydroisoquinolines and tryptolines

New method using arenium-ion catalysis to effectively transforms quaternary silanes into a variety of functional derivatives

Iminoreductases are efficiently used to reduce cyclic imines in deep eutectic solvents and glycerol

Catalyst- and substrate-controlled transformation via cyclization of indole-functionalized alkynols

Reaction based on dual nickel/photoredox catalysis shows ligand-controlled regioselectivity

Highlights from Chemistry Europe, ACES, and GDCh journals

Ammoxidation of benzyl alcohol enabled by multiple vacancies

Pyridoxal 5'-phosphate-dependent Mannich cyclase can deuterate a diverse range of amino acids

Method based on enzymatic resolution of α-sulfinyl esters followed by decarboxylative functionalization