Overview of the latest issue of Angewandte Chemie

Angewandte Chemie 25/2019: Giving Directions

Greater Information Storage in Synthesized DNA
DNA building blocks encode twice as much information

Designing Molecules with Protein-Like Functions
Exploring the functional consequences of protein backbone alteration in ubiquitin

DNA Barcodes Help to Screen Drug Candidates
Diverse collection of macrocycles attached to DNA barcodes synthesized to find lead structures that inhibit disease-relevant proteins

Rare Possibility to Fight Cancer Investigated
Iridium-Aspirin conjugates target both mitochondria and the immune system to combat cancer

Milestone for Structural Chemistry
Cambridge Structural Database (CSD) now contains one million crystal structures

Better In Vitro Visualization of Biomolecules
Fluorescent pyridazines provide good signal-to-noise ratio

ATP Could Provide a Safety Mechanism against Cancer
ATP and other nucleoside triphosphates inhibit a tumor-relevant transcription factor

Great People Don’t Need to Show Off
EuChemS Organic Division President Gianluca Farinola about his fascination for organic chemistry and the importance of young scientists

Single Cells Get Their Shells
Nanocomposite exoskeleton makes mammalian cells more resilient and incorporated inorganic building blocks provide many possibilities