In this issue, G. J. Snyder et al. review how chemists use their intuition in the design of thermoelectric materials. What is the influence of local bonding interactions? The Highlight deals with omniphobic silicon brushes (S. Wooh, D. Vollmer). In his Editorial, G. Helmchen looks back on 50 years of Cahn–Ingold–Prelog specifications for molecular chirality, originally published in Angewandte.

In the Communications section, H. Sato et al. write on the modelling and synthesis of boron-doped palladium catalysts for oxygen reduction (see picture). D. Yang et al. found the local unfolding of fatty acid binding protein to allow ligand entry for binding. M. Szostak et al. describe a synthesis of biaryls through the Ni-catalyzed Suzuki–Miyaura coupling of amides by C–N bond cleavage.

• Angewandte Chemie 24/2016: Chirality Now and Then,
  Angew. Chem. Int. Ed. 2016, 55 (24).