In his Nobel lecture, J. E. Rothman discusses the principle of membrane fusion in the cell. How do vesicles serve the cell’s internal physiological needs? Fellow Nobel laureate T. C. Südhof explains the molecular machinery of neurotransmitter release: How do the synaptic vesicle and the plasma membrane undergo rapid fusion and how this process is spatially organized?

In the Communications section, J. A. Dumesic et al. describe how to engineer catalyst microenvironments for the metal-catalyzed hydrogenation of biologically derived platform chemicals (pictured). L. Cronin et al. present 3D-printed hydrothermal reactionware for discovery, optimization, and scale-up. J. Chen et al. produced MoS₂ nanoflowers with expanded interlayers as high-performance anodes for sodium-ion batteries. P. J. Dyson et al. report on a metal-free catalyst for the chemoselective methylation of amines using CO₂ as a carbon source.

• Angewandte Chemie 47/2014: Molecular Machinery,
  Angew. Chem. Int. Ed. 2014, 53 (47).