In this issue, K. B. Sharpless et al. review the sulfur(VI) fluoride exchange reaction (SuFEx): In what way is it another good reaction for click chemistry? The Highlight deals with the remote functionalization of C–H bonds (M. Beller et al.).

In the Communications section, A. Friedler et al. describe a tandem in situ peptide cyclization through trifluoroacetic acid cleavage (see picture). S.-G. He et al. report on the thermal methane conversion to formaldehyde by single platinum atoms located in cluster anions. C. J. Yang et al. succeeded in the preparation of a nanomicelle for real-time imaging and NIR cancer therapy. Sharpless, Fokin et al. present a synthesis of polysulfates by applying SuFEx click chemistry.

• Angewandte Chemie 36/2014: Click to Synthesize,
  Angew. Chem. Int. Ed. 2014, 36.