Professor Barry M. Trost, Stanford University, USA has been awarded the August Wilhelm von Hofmann Medal by the German Chemical Society (Gesellschaft Deutscher Chemiker, GDCh). The award was presented during the opening ceremony of the 5th EuCheMS Chemistry Congress, which takes place in Istanbul and is organized by the European Association for Chemical and Molecular Sciences (EuCheMS).
The August Wilhelm von Hofmann Medal is awarded every two years and recognizes outstanding achievements in chemistry, in particular by scientists working outside of Germany.
Barry Martin Trost was born on June 13, 1941 in Philadelphia, PA, USA. He received his bachelor’s degree from the University of Pennsylvania, PA, in 1962 and his PhD from the Massachusetts Institute of Technology (MIT), Cambridge, USA, in 1965 under the supervision of H. O. House. He was appointed Professor of Chemistry at Stanford University in 1987 and Job and Gertrud Tamaki Professor in the School of Humanities and Sciences in 1990.
Among many other honors, Professor Trost was awarded the Nagoya Medal in 2008 and is a member of the National Academy of Sciences.
The focus of his research is developing reactions and reagents for organic synthesis. His achievements include the development of the eponymous Tsuji–Trost reaction, a palladium-catalyzed alkylation in allylic positions, and the Trost ligand.
Dr. Thomas Geelhaar, President of the GDCh and Merck KG, Darmstadt, Germany, presents the award.
Selected Publications:
- Palladium-Catalyzed Enantioselective Allylic Alkylations through C–H Activation,
Barry M. Trost, David A. Thaisrivongs, Etienne J. Donckele,
Angew. Chem. Int. Ed. 2013, 52, 1523–1526.
DOI: 10.1002/anie.201207870 - Regio- and Enantioselective Synthesis of Pyrrolidines Bearing a Quaternary Center by Palladium-Catalyzed Asymmetric [3 + 2] Cycloaddition of Trimethylenemethanes,
Barry M. Trost, Tom M. Lam, Melissa A. Herbage,
J. Am. Chem. Soc. 2013, 135, 2459–2461.
DOI: 10.1021/ja312351s - Development of Zn–ProPhenol-Catalyzed Asymmetric Alkyne Addition: Synthesis of Chiral Propargylic Alcohols,
Barry M. Trost, Mark J. Bartlett, Andrew H. Weiss, Axel Jacobi von Wangelin, Vincent S. Chan,
Chem. Eur. J. 2012, 18, 16498–16509.
DOI: 10.1002/chem.201202085 - Asymmetric Catalytic Alkynylation of Acetaldehyde: Application to the Synthesis of (+)-Tetrahydropyrenophorol,
Barry M. Trost, Adrien Quintard,
Angew. Chem. Int. Ed. 2012, 51, 6704–6708.
DOI: 10.1002/anie.201203035 - New synthetic reactions. Allylic alkylation,
Barry M. Trost , Terry J. Fullerton,
J. Am. Chem. Soc. 1973, 95, 292–294.
DOI: 10.1021/ja00782a080
