Carolyn R. Bertozzi, University of California (UC), Berkeley, USA, has been awarded the Heinrich Wieland Prize 2012. The prize is awarded by the Boehringer Ingelheim Foundation for outstanding research on biologically active molecules and systems and their clinical impact in chemistry, biochemistry, and physiology and is endowed with € 50,000. Bertozzi wins the prize for her work on the biological functions of cellular sugars, including the sugar modifications associated with cancer, inflammation, and infection.
The prize was awarded at a public ceremony at the Ludwig Maximilian University of Munich, Germany, on October 18, 2012, where Bertozzi presented a prize lecture on the challenges and opportunities of in vivo chemistry.
Carolyn Bertozzi studied chemistry at Harvard University, USA, and UC Berkeley and obtained her Ph.D. at UC Berkeley in 1993. She did postdoctoral work at the University of California, San Francisco, USA, before joining the UC Berkeley faculty in 1996. She is currently Professor of Chemistry and Professor of Cell and Molecular Biology at UC Berkeley and an investigator of the Howard Hughes Medical Institute, USA.
Bertozzi’s research focuses on glycosylation—the process in cells by which sugars are added to proteins or other molecules. She is a pioneer in the field of bioorthogonal chemistry and has developed bioorthogonal reporters, which can be added as a marker molecule to cell surface sugars and can help differentiate healthy from diseased cells, thus paving the way for new diagnoses and therapies.
Bertozzi serves on the International Advisory Board of Angewandte Chemie and will deliver a talk at the symposium celebrating 125 years of Angewandte Chemie in Berlin, Germany, on March 12, 2013.
- Synthesis of Heterobifunctional Protein Fusions Using Copper-Free Click Chemistry and the Aldehyde Tag,
Jason E. Hudak, Robyn M. Barfield, Gregory W. de Hart, Patricia Grob, Eva Nogales, Carolyn R. Bertozzi, David Rabuka,
Angew. Chem. Int. Ed. 2012, 51(17), 4161–4165.
DOI: 10.1002/anie.201108130 - Imaging the Sialome during Zebrafish Development with Copper-Free Click Chemistry,
Karen W. Dehnert, Jeremy M. Baskin, Scott T. Laughlin, Brendan J. Beahm, Natasha N. Naidu, Sharon L. Amacher, Carolyn R. Bertozzi,
ChemBioChem 2012, 13(3), 353–357.
DOI: 10.1002/cbic.201100649 - Bioorthogonal Chemistry: Fishing for Selectivity in a Sea of Functionality,
Ellen M. Sletten, Carolyn R. Bertozzi,
Angew. Chem. Int. Ed. 2009, 48(38), 6974–6998.
DOI: 10.1002/anie.200900942
Also of interest:
Heinrich Wieland: Naturforscher, Nobelpreisträger und Willstätters Uhr
,
Sibylle Wieland, Anne-Barb Hertkorn, Franziska Dunkel (Eds.),
Wiley-VCH, Weinheim, Germany, 2008.
ISBN: 978-3-527-32333-3
Feodor Lynen
,
Heike Will,
Wiley-VCH, Weinheim, Germany, 2011.
ISBN: 9783527328932- C. Bertozzi Awarded 2011 Emanuel Merck Lectureship
Carolyn Bertozzi, University of California, Berkeley, USA, has been awarded the Emanuel Merck Lectureship - Invention and Innovation Award
Wiley-VCH author and Angew. Chem. Advisory Board member, Carolyn Bertozzi will receive this year’s $500,000 Lemelson-MIT Prize.
