In this issue, E. Y. Chekmenev et al. review enabling clinical technologies for hyperpolarized ¹²⁹Xe magnetic resonance imaging and spectroscopy, and M. Ruck et al. discuss inorganic syntheses based on reactions of ionic liquids and deep eutectic solvents. The Minireview deals with the detection of pharma-molecule transport across bacterial membranes by electrochemistry and bioanalytical methods (S. Kuss).

In the original research section, Y. H. Rhee et al. present a palladium-catalyzed asymmetric decarboxylative addition of β-keto acids to heteroatom-substituted allenes (see picture). J. P. Attfield et al. succeeded in double double to double perovskite transformations in quaternary manganese oxides. D. Lee et al. synthesized a superatom-in-superatom [RhH@Ag₂₄(SPhMe₂)₁₈]²⁻ nanocluster. A. Heckel et al. describe how to control coagulation in blood with red light.

• Angewandte Chemie 41/2021: Enabling Chemistry,
  Angew. Chem. Int. Ed. 2021, 60 (41).