In this issue, A. Kirschning and B. König et al. review coenzymes and their role in the evolution of life and excited-state anions in organic transformations, respectively. The Minireviews deal with the combination of DNA origami with synthetic polymers (U. S. Schubert et al.) and meso-substituents in tricarbocyanine dyes for diverse biomolecular probes and materials (S. I. Pascu).

In the original research section, Y. Tang et al. describe an intramolecular electric field construction in a metal phthalocyanine as a dopant-free hole transport material for perovskite solar cells. W. Tang et al. succeeded in the asymmetric hydroesterification of diarylmethyl carbinols. P. J. Sadler et al. tracked reactions of asymmetric organo-osmium transfer hydrogenation catalysts in cancer cells (see picture), and L. Li et al. observed efficient separation of acetylene and carbon dioxide in a decorated zeolite.

• Angewandte Chemie 12/2021: Evolution,
  Angew. Chem. Int. Ed. 2020, 60 (12).