In this issue, R. Ruiz-Molina et al. review the chemistry of catechol-based adhesion. What inherent and external parameters influence the performance of these materials? In Minireviews, W. Lin et al. discuss the role of nanoparticle-mediated immunogenic cell death in cancer immunotherapy, and R. G. Carter et al. summarize recent syntheses and strategies toward polycyclic gelsemium alkaloids. The Highlight deals with microcrystal electron diffraction (microED) for small-molecule structure determination (T. Kunde, B. M. Schmidt).

In the Communications section, H. Schnöckel et al. investigate the reaction energy and reactivity of P–Cl bond reductions with Mg(I) halides vs. magnesium metal. J. Wang et al. developed an intrinsic flame-retardant organic electrolyte for safe lithium–sulfur batteries. L. J. Gooßen et al. succeeded in the decarboxylative ipso amination of activated benzoic acids.

• Angewandte Chemie 3/2019: The Chemistry behind,
  Angew. Chem. Int. Ed. 2019, 58 (3).