In this issue, U. Rosenthal reviews reactions of Group 4 metallocene bis(trimethylsilyl)acetylene complexes with nitriles and isonitriles. How can they be applied in syntheses? In a Minireview, L. Ackermann et al. discuss late-stage peptide diversification by position-selective C–H activation. The Highlight addresses the question whether Meisenheimer complexes in S_NAr reactions are intermediates or transition states (A. J. J. Lennox). S. A. Matlin et al. share a Viewpoint on equality, diversity, and inclusion in the chemical sciences.

In the Communications section, F. Göricke and C. Schneider present a palladium-catalyzed enantioselective addition of chiral metal enolates to in situ generated ortho-quinone methides (see picture). A. Robert et al. found that magnetite Fe₃O₄ has no intrinsic peroxidase activity and is probably not involved in Alzheimer’s oxidative stress. H. Cheng et al. used palladium phosphide as a stable and efficient electrocatalyst for overall water splitting.

• Angewandte Chemie 45/2018: Versatility,
  Angew. Chem. Int. Ed. 2018, 57 (45).