In this issue, A. Eychmüller et al. review modern inorganic aerogels. How can nanoparticles be used to create materials with designed properties? In a Minireview, R. M. Strongin et al. discuss fluorescent probes with multiple binding sites for the discrimination of amino acids. The Highlight deals with a nucleoside analogue that selectively inhibits bacterial RNA polymerase (M. F. Chellat and R. Riedl).

In the Communications section, M. Weingarth et al. describe the supramolecular organization and functional implications of K⁺ channel clusters in membranes (see picture). J. Wang et al. write about preorganization and cooperation for highly efficient and reversible capture of low-concentration CO₂ by ionic liquids. M. Alcarazo et al. succeeded in the regio- and stereoselective chlorocyanation of alkynes.

• Angewandte Chemie 43/2017: Designing Properties,
  Angew. Chem. Int. Ed. 2017, 56 (43).