US scientists revealed that the sirtuin SIRT6 is not a deacetylase but a long-chain fatty-acyl hydrolase

Acetyl or Myristoyl: That is the Question

DNA Logic Gates for Metal-ion Sensing
Electronic logic gates made from DNA in conjunction with metal-ion sensing could be used for point-of-care sensing devices

Preventing Geldanamycin’s Toxicity
Novel 19-substituted benzoquinone ansamycins inhibit heat shock protein 90 without causing toxic effects in vitro

Long Wavelength Fluorescein Analogues
Modification of fluorescene leads to analogues with better photo-physical characteristics

Lactimidomycin – No Effect on Cell Motility but Still Cytotoxic
Synthesis and biological re-evaluation of the cytotoxic effects of Lactimidomycin and its progeny in cancer cells

Assisting C−H Activation
Detailed study into the mechanism for carboxylate-assisted C−H bond activation at Pd(IV) centers has been undertaken

Magnetic Catalytic Recycling
A magnetic can be used to recycle catalytic nanoparticles that could be used for an important and widely used set of reactions

Green Oxidations on Graphene
Graphene as an aerobic oxidation carbocatalyst derived from natural resources

Machine-Assisted Flow Synthesis
Flow-based syntheses to accelerate multistep routes to highly complex, medically relevant compounds have been evaluated

Novel Therapeutic Target for Pancreatic Cancer
A non-canonical metabolism of the amino acid glutamine sustains pancreatic ductal adenocarcinoma’s growth