A new imidazopyridine amide derivative kills drug-resistant tuberculosis strains through a novel mechanism

A Novel Way to Fight Tuberculosis

Probing Enzyme Activity
The activity of different enzymes was investigated by using newly developed probes for 19F NMR/MRI imaging

Matrix Metalloproteinase Inhibitor
A potent and selective matrix metalloproteinase inhibitor has been developed by the conjugation of cyclam and marimastat

Improving the Synthesis of Perylene Diimide Dimers
A combination of C–C homocoupling and C–H activation doubles the yields of perylenediimide dimers

No Caffeine During Pregnancy?
Caffeine consumption during pregnancy alters brain’s development of mice

Boosting Endocannabinoids
LM-4131 is a novel anxiolytic compound that acts by selectively stimulating endocannabinoids’ activity

Molecular Containers in the Gas Phase
Noncovalent interactions between several protonated amines and an original ditopic receptor, nor-seco-cucurbit[10]uril, are investigated

Stereoselective Total Synthesis of Attenols A and B
A highly convergent total synthesis of attenols A and B utilizing a double alkylation tosylmethyl isocyanide (TosMIC) strategy to construct the spiro acetal segment

Metabolic Monitoring
Fluorescent sensor will allow to detect and monitor a ubiquitous metabolite made by all living cells and involved in many disease states

Angewandte Chemie 34/2013: Celebrating Liquid Crystals
Overview of the latest issue of Angewandte Chemie