The activity of different enzymes was investigated by using newly developed probes for 19F NMR/MRI imaging
Probing Enzyme Activity
Matrix Metalloproteinase Inhibitor
A potent and selective matrix metalloproteinase inhibitor has been developed by the conjugation of cyclam and marimastat
Improving the Synthesis of Perylene Diimide Dimers
A combination of C–C homocoupling and C–H activation doubles the yields of perylenediimide dimers
No Caffeine During Pregnancy?
Caffeine consumption during pregnancy alters brain’s development of mice
Boosting Endocannabinoids
LM-4131 is a novel anxiolytic compound that acts by selectively stimulating endocannabinoids’ activity
Molecular Containers in the Gas Phase
Noncovalent interactions between several protonated amines and an original ditopic receptor, nor-seco-cucurbit[10]uril, are investigated
Stereoselective Total Synthesis of Attenols A and B
A highly convergent total synthesis of attenols A and B utilizing a double alkylation tosylmethyl isocyanide (TosMIC) strategy to construct the spiro acetal segment
Metabolic Monitoring
Fluorescent sensor will allow to detect and monitor a ubiquitous metabolite made by all living cells and involved in many disease states
Angewandte Chemie 34/2013: Celebrating Liquid Crystals
Overview of the latest issue of Angewandte Chemie
Resolving Asymmetric Epoxidations
An enantioselective route to form epoxides by using kinetic resolution techniques has been developed