Phenanthrene/pyrene hybrid microparticles can stand in for cosmic dust rich in polycyclic aromatic hydrocarbons (PAHs)

A Synthetic Mimic for Cosmic Dust

Three-Component Reaction Gives Substituted Pyridines
Deoxygenative transformation involving alcohols, styrenes, and cyanopyridines

First Thionyl Chloride Adduct with a Main-Group Element Lewis Acid
Adducts of tris(pentafluoroethyl)gallium and indium with weak donor molecules synthesized

Rapid Photochemical Synthesis of Peptide Thiolactones
Unprotected peptides cyclized via an acyl thiol–ene reaction

Electrochemical Reduction of Disulfides
Vitamin B12-catalyzed transformation of a wide range of substrates, from small molecules to proteins

Can Large Language Models Predict Inorganic Syntheses?
Fine-tuned large language models (LLMs) found to perform similar to or better than specialized machine learning models for certain chemical tasks

Modular Acrylamide Synthesis
Palladium-catalyzed hydroaminocarbonylation of acetylene

Straightforward Path to Cyanoformamides
Dimethylphenylsilylcyanide used as a cyanide source for addition to widely available isocyanates

August Wilhelm von Hofmann Medal for David A. Leigh
Pioneering achievements in the field of nanoscience and work as an ambassador for chemistry honored

Half-Curcumin-Based Chemiluminescence Probes
Probe detects quasi-stable oxidized proteins; could be used for liver imaging or blood tests