Five new heterocyclic ring systems that could have uses in medicinal chemistry

New Tetracyclic Ring Systems Synthesized

More Sustainable Semiconductor Manufacturing
Merck and Intel join forces with European researchers to advance sustainable semiconductor technologies through AI

Silylation and Germylation of Azauracils
New protocol can be used for the late-stage functionalization of complex, drug-like molecules under mild conditions

Technip Energies, Alterra, and Neste Offer Standardized Recycling Plants
The companies say they are offering a standardized technology to make plastic recycling more efficient and cost-effective

New Cleavable Linker Design for Targeted Drug Therapy
Physiological thiol gradient between extra- and intracellular areas used to trigger novel cleavable linkers

Practical Path to Dihydrobenzisoxazoles
Partial nitro reduction of methyl 2-nitrobenzoates followed by base-mediated cyclization, alkylation, and reduction gives useful bicyclic compounds

Hazardous Chemicals Found in European Cosmetics
Inspections found banned chemicals, such as perfluorononyl dimethicone and D4/D5 siloxanes, in cosmetics like eyeliners, lipliners, and hair conditioners

Dinitrogen Turned into a Photoswitch
First lanthanide N2 photoswitch shows isomerization between side-on and end-on coordination

Promising Scaffold Material for Cultured Pork
Hybrid cultivated meat products combine traditional meat with alternative protein sources, like plant-based proteins, to enhance sensory and nutritional qualities

Twisting Alkyne Cycloparaphenylenes into a Molecular Pinwheel
Strain-promoted alkyne cyclotrimerization gives curved carbon nanostructures