Fine-tuned large language models (LLMs) found to perform similar to or better than specialized machine learning models for certain chemical tasks

Can Large Language Models Predict Inorganic Syntheses?

Modular Acrylamide Synthesis
Palladium-catalyzed hydroaminocarbonylation of acetylene

Straightforward Path to Cyanoformamides
Dimethylphenylsilylcyanide used as a cyanide source for addition to widely available isocyanates

August Wilhelm von Hofmann Medal for David A. Leigh
Pioneering achievements in the field of nanoscience and work as an ambassador for chemistry honored

Half-Curcumin-Based Chemiluminescence Probes
Probe detects quasi-stable oxidized proteins; could be used for liver imaging or blood tests

Hydride-Free Copper Nanocluster for Catalysis
Atomically precise, luminescent copper nanocluster can promote photoinduced C–C coupling reactions

European Inventor Award: Carol Robinson Named Lifetime Achievement Laureate
British chemist made important contributions to drug development and biochemical research and shows a strong commitment to mentorship

Solvent-Promoted Total Syntheses of Sesquiterpenoid Dimers
Gochnatiolide D and ainsliadimer A prepared via a one-pot sequence using hexafluoroisopropanol (HFIP) as the solvent

Iron-Catalyzed Cleavage of Allylic Alcohols
Regiospecific Cα–Cβ cleavage under modified aerobic Mukaiyama hydration conditions

Iridium-Fullerene Complexes for Photodynamic Therapy
Microtubule polymerization and dual reactive oxygen species regulation against cancer