Diterpenoid with a 5–5–6–6–3-fused pentacyclic carbon skeleton

First Total Synthesis of (+)-Pedrolide

Emissions of Banned Ozone-Depleting Chlorofluorocarbons Increased
Rising emissions of five chlorofluorocarbons (CFCs) observed between 2010 and 2020

Microplastics Affect the Gut Microbiomes of Seabirds
Microplastics associated with decreases in beneficial bacteria and increases in pathogens

Angewandte Chemie 16/2023: Innovation Watch
Overview of the latest issue of Angewandte Chemie

Tri-Enzymatic Cascade for the Synthesis of an Important Chiral Drug Intermediate
Efficient production of L-2-aminobutyrate from L-threonine

Promising Results for Nasal COVID-19 Vaccine in Hamster Trial
Hamster trial finds live-attenuated vaccine candidate that is administered nasally to be more effective than conventional vaccines

Advancing Development of Personalized Antibody-Drug Conjugate Therapies for Solid Tumors
BioNTech has obtained exclusive licenses from DualityBio for two investigational antibody-drug conjugate assets that target a wide range of human cancers

Convergent Total Synthesis of (+)-Ineleganolide
Natural product with a highly oxidized framework and a central seven-membered ring

Mn-Catalyzed Allylation of Benzoates
Simple manganese catalyst for ortho-C–H allylations, which can be combined with a decarboxylation to access allylarenes

Triazole-Substituted Ethisterones as Anticancer Compounds
Single-step syntheses of derivatives with promising cytotoxic activities