Gisbert Schneider and co-workers, Goethe-University, Frankfurt, Germany, report on target profile prediction to identify cross-activities of peroxisome proliferator-activated receptor (PPAR) and farnesoid X receptor (FXR).
Targeted Identification
Deracemize to Reracemize
Deracemization of mandelic acid to optically pure L-phenylglycine via a redox-neutral biocatalytic cascade.
Structure-Based Ligand Design
Freya Klepsch and Gerhard F. Ecker, University of Vienna, Austria, highlight the Impact of the recent mouse P-glycoprotein structure for structure-based ligand design.
Army Cleans Up Its Act
Newly-developed agents allow all-weather hydrogen peroxide-based decontamination of chemical, biological, radiological and nuclear contaminants.