Method can be used across a broad range of different enzymes and metabolites

Machine-Learning Model Predicts Enzyme-Substrate Pairs

Photochemical Deracemization of 3-Substituted Oxindoles
Racemate successfully converted into enantiomerically pure or enriched material in the presence of a chiral benzophenone catalyst

Total Synthesis of Chaetoglobin A
Dimeric alkaloid from a fungus has a chiral axis connecting two azaphilone systems

Gold-Catalyzed Reaction Gives Antitumor-Active Spirocyclic Oxindoles
Formal cycloaddition reaction of terminal alkynes or ynamides with isatin-derived ketimines

Synthesis of Bis-Benzofulvenes
Route from gem-dibromoolefins via bromobenzofulvene intermediates

Phosphine Oxide-Substituted Cyclam Ligand Synthesized
Ligand with high selectivity for Cu(II) over competing divalent cations

Nickel-Catalyzed Coupling of Heteroarenes and Arenols
Pivalic anhydride used as an in-situ activating reagent in C−H/C−OH coupling

Alkene Insertion into Carbon–Halogen Bonds Enabled by Aggregation
Ionic insertion without additional catalysts or promoters

BASF’s Chemovator Welcomes External Startups to Incubation Program
Start-ups in the areas of sustainability, process optimization, research, service optimization, and next-generation materials supported

Liver-Targeted Nanoparticles for Treating Type 2 Diabetes
Drug-loaded reactive oxygen species (ROS) scavengers could restore insulin sensitivity