Prodrugs selectively activated by high levels of reactive oxygen species in cancer cells could lead to more active and less toxic treatments

Hydrogen Peroxide Helps Target Cancer

Central Chirality by E/Z Photoismomerization
First example of the induction of point chirality in which two of the substituents around an sp3 carbon atom are geometric isomers

Salinomycin Biosynthesis in Detail
The timing of the key steps in antibiotic and potential anti-cancer compound, salinomycin's biosynthesis has been uncovered

University World Rankings
TimesHE ranks the American universities top in league table headed by Caltech with Harvard and Stanford second and third

Pretzels with Porphyrin
A [2]catenane and a pretzelane that incorporate porphyrin by axial ligation have been made by researchers in China

Nagoya Medal of Organic Chemistry Awarded
The Nagoya Medal of Organic Chemistry has been awarded to Eric Jacobsen (Gold Medal) and Keiji Tanino (Silver Medal)

C. Bertozzi Awarded 2011 Emanuel Merck Lectureship
Carolyn Bertozzi, University of California, Berkeley, USA, has been awarded the Emanuel Merck Lectureship

Uncovering Invisible Biomarkers
Biomarkers previously invisible to mass spectrometry can now be detected with nanoparticles that concentrate and protect

Get Knotted
A complex pentafoil knot comprising, not of DNA as were previous knots, but a synthetic organometallic system

Inhibiting Biofilm Formation
Small molecules that inhibit biofilm development useful in treatment of chronic biofilm infections in combination with standard antibiotics