The enantioselective synthesis of alkaloids, using a tricyclic (R)-phenylglycinol-derived lactam scaffold is reported.
An in-depth look at a selected research article and its significance.

Scaffold Synthesis

Long Fuse
George Whitesides describes how dots of salt can be used to transmit information for times electronics or batteries fail.

Dot Products
Enzymatic generation of quantum dots could lead to news ways of analyzing milk by fluorescence spectroscopy.

Self-Assembling Devices
Design strategy with side-chain incompatibility provides promise for the realization of much greater photoconducting output.

Layered Footballs
A new variant of fullerenes has been made: a two-dimensional fullerene with layers that acts like a metal

Improving Kinase Inhibitors
Resorcylic acid lactone (RAL) representing a unique pharmacophore was edited to improve the properties and diversify the scaffold.

Puzzling Pyridine Problem Probed
Mixing dichloromethane with pyridine derivatives under ambient conditions provides a surprising result.

Understanding the APJ Receptor Binding Site
Exploring the RPRL motif of apelin-13 through molecular simulation and biological evaluation of cyclic peptide analogues

Small But Super
Lightweight, handy magnets could allow high-resolution NMR spectroscopy to develop into a portable analytical technique.

Small, Fast, and High Contrast
Imaging technique enables studies on the dynamics of nanocatalysts at unprecedented spatial and temporal resolution